I believe the most comfortable way to travel is by train. You have conveniences such as spacious washrooms, food/beverages, comfortable seats and some terrific views along the way. We have traveled in Canada by the VIA Rail system. I can say that the two times we have gone from Windsor to Toronto have been easier than if we went by bus. We did use the GO Rail system to travel to Niagara Falls from Toronto. We did take the bus on our last trip from Chattanooga to Detroit, and that was an adventure I recommend to anyone. So I am going to say trains if you have time to get from place to place.


